Somno

Somno is exogenous melatonin. Melatonin is a naturally occurring sleep inducing hormone. Physiologically, melatonin secretion increases soon after the onset of darkness, peaks at 2-4 am and diminishes during the second half of the night. It is a very natural way of inducing sleep. Unlike some anxiolytics, Somno does not cause hangover like feeling.

No Somno does not cause addiction.

Some drugs may interfere with the metabolism of Somno and vice vera. Melatonin levels may be subject to change due to some antidepressants. Hence medical advice may be taken.

Cytochrome P450 isoenzymes and CYP1A2 are involved in the metabolism of melatonin and consequently other drugs that inhibit or induce these isoenzymes may affect melatonin levels. Melatonin should not be taken with fluvoxamine, methoxsalen, cimetidine, or oestrogens, all of which increases the melatonin concentrations through inhibition of its metabolism. Tobacco smoking may decrease melatonin levels due to induction of CYP1A2. Cigarette smoking may decrease melatonin levels due to induction of CYP1A2. CYP1A2 inducers such as carbamazepine and rifampicin may give rise to reduced plasma concentrations of melatonin. Alcohol should not be taken with melatonin, because it reduces the effectiveness of melatonin on sleep. Melatonin may enhance the sedative properties of benzodiazepines and non-benzodiazepine hypnotics, such as zaleplon, zolpidem and zopiclone.

If taken in the morning, Somno will likely make the individual feel sleepy or drowsy. If Somno is taken regularly in the morning, it may shift the circadian rhythm. For the treatment of insomnia, patients should take Somno at night only.